منابع مشابه
P11: The Role of Aquaporin-4Receotors in Mesial Temporal Epilepsy
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متن کاملAquaporin Evolution in Fishes
Aquaporins represent a primordial group of transmembrane solvent channels that have been documented throughout the living biota. This facet alone emphasizes the positive selection pressure for proteins associated with intracellular fluid homeostasis. Amongst extant Eukaryota the highest gene copy number can be found in plants and teleosts, a feature that reflects the genomic duplication history...
متن کاملThe aquaporin water channels.
The topic of my talk, the aquaporins, is something that we have been studying in our lab for the last 15 years. It is not something that I anticipated when starting my career. In fact, I am a hematologist, but in science, sometimes what we find is not what we are looking for. A typical middle-aged man, I weigh 75 kg, of which 50 are water. This is something that we all share. Water is the major...
متن کاملAquaporin Protein-Protein Interactions
Aquaporins are tetrameric membrane-bound channels that facilitate transport of water and other small solutes across cell membranes. In eukaryotes, they are frequently regulated by gating or trafficking, allowing for the cell to control membrane permeability in a specific manner. Protein-protein interactions play crucial roles in both regulatory processes and also mediate alternative functions s...
متن کاملAquaporin-4 autoimmunity
Neuromyelitis optica (NMO) and a related spectrum of inflammatory CNS disorders are unified by detection of a serum autoantibody specific for the aquaporin-4 (AQP4) water channel, which is abundant in astrocytic foot processes. The classic clinical manifestations of NMO are optic neuritis and longitudinally extensive transverse myelitis. Newly recognized manifestations of AQP4 autoimmunity incl...
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ژورنال
عنوان ژورنال: Kobunshi
سال: 2002
ISSN: 0454-1138,2185-9825
DOI: 10.1295/kobunshi.51.513